![]() In the hospital setting, this includes Clinical Laboratory Scientists, Registered Nurses, Nurse Practitioners, Physician Assistants, Physicians, Respiratory Tech. PERSONNEL Intended for use by clinical personnel who have received training and demonstrated competency in this procedure. SCOPE This waived test procedure is intended for use in the Radiology clinics, in both the inpatient and the outpatient settings. Creatinine measurements are used in the diagnosis and treatment of renal diseases, in monitoring renal dialysis, and as a calculation basis for measuring other urine analytes. The i-STAT1 creatinine assay agrees with IDMS-traceable Standard Reference Material SRM 967. The i-STAT Creatinine test is used for the quantitative determination of creatinine (crea) in whole blood on the i-STAT handheld. The abbreviated MDRD equation has been developed, to facilitate calculation of the GFR:GFR (mL/min per 1.73 m 2 1.21) 186.3 x Serum Creatinine (exp-1.154) x Age (exp-0.203) x (0.742 if female) x (1.21 if african american)To use this formula to gain an idea of your GFR, you should input your age, gender, race and you also need creatinine. The liberated hydrogen peroxide is oxidized at the platinum electrode to produce a current which is proportional to the sample creatinine concentration. Hydroxyurea and toxic acetaminophen levels above 1.32mmol/l elevate I Stat creatinine levels, test using another method. The oxidation of sarcosine, catalyzed by the enzyme sarcosine oxidase, produces hydrogen peroxide (H2O2). Creatin is then hydrolyzed to sarcosine in a reaction catalyzed by the enzyme creatine amidohydrolase. Creatinine is hydrolyzed to creatine in a reaction catalyzed by the enzyme creatinine amidohydrolase. Director’s Signature:_ Date:_ Clinical Laboratories Point of Care Testing i-STAT POCT CREATININE TESTING PURPOSE AND PRINCIPLE The i-STAT1 system is a battery powered portable analyzer that utilizes single-use disposable cartridges to analyze creatinine using 65uL of venous whole blood collected in a green top vacutainer tube. Urine Creatinine Normal Range Regular (Random) Test Urine creatinine test results are usually reported in mg/dL (milligrams per deciliter).
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